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Immunosuppressive capacity of circulating MDSC predicts response to immune checkpoint inhibitors in melanoma patients

PURPOSE: Although the treatment of advanced melanoma patients with immune checkpoint inhibitors (ICI) significantly increased the therapeutic efficiency, many patients remain resistant to ICI that could be due to immunosuppression mediated by myeloid-derived suppressor cells (MDSC). These cells are...

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Detalles Bibliográficos
Autores principales: Petrova, Vera, Groth, Christopher, Bitsch, Rebekka, Arkhypov, Ihor, Simon, Sonja C. S., Hetjens, Svetlana, Müller, Verena, Utikal, Jochen, Umansky, Viktor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968744/
https://www.ncbi.nlm.nih.gov/pubmed/36860876
http://dx.doi.org/10.3389/fimmu.2023.1065767