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Oscillatory shear stress promotes vein graft intimal hyperplasia via NADPH oxidase-related pathways

BACKGROUND: Uncontrolled intimal hyperplasia (IH) after autologous saphenous vein grafting triggers a high restenosis rate; however, its association with the activation of NADPH oxidase (NOX)-related pathways is unclear. Here, we investigated the effects and mechanism of oscillatory shear stress (OS...

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Detalles Bibliográficos
Autores principales: Yao, Guoqing, Li, Huanhuan, Zuo, Xiangyi, Wang, Chunkai, Xiao, Yelei, Zhao, Yu, Wang, Xuehu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968757/
https://www.ncbi.nlm.nih.gov/pubmed/36860953
http://dx.doi.org/10.3389/fsurg.2023.1073557