Pilot dose-ranging of rhIGF-1/rhIGFBP-3 in a preterm lamb model of evolving bronchopulmonary dysplasia

BACKGROUND: Low levels of insulin-like growth factor-1 (IGF-1) protein in preterm human infants are associated with bronchopulmonary dysplasia (BPD). We used our preterm lamb model of BPD to determine: (1) dosage of recombinant human (rh) IGF-1 bound to binding protein 3 (IGFBP3) to reach infant phy...

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Detalles Bibliográficos
Autores principales: Albertine, Kurt H., Dahl, Mar Janna, Rebentisch, Andrew, Dawson, Elaine, Nabi, Akbar, Bowen, Sydney, Miers, Cindy, Wang, Zhengming, Yang, Haixia, Yu, Baifeng, Null, Donald M., Keefe, Dennis, Chung, J-K, Zhou, Z, Barton, Norman, Carey, Galen, Ward, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968819/
https://www.ncbi.nlm.nih.gov/pubmed/36030318
http://dx.doi.org/10.1038/s41390-022-02272-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968819/
https://www.ncbi.nlm.nih.gov/pubmed/36030318
http://dx.doi.org/10.1038/s41390-022-02272-9

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