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A need for exhaustive and standardized characterization of ion channels activity. The case of K(V)11.1
hERG, the pore-forming subunit of the rapid component of the delayed rectifier K(+) current, plays a key role in ventricular repolarization. Mutations in the KCNH2 gene encoding hERG are associated with several cardiac rhythmic disorders, mainly the Long QT syndrome (LQTS) characterized by prolonged...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968853/ https://www.ncbi.nlm.nih.gov/pubmed/36860515 http://dx.doi.org/10.3389/fphys.2023.1132533 |