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C. elegans orphan nuclear receptor NHR-42 represses innate immunity and promotes lipid loss downstream of HLH-30/TFEB

In recent years, transcription factors of the Microphthalmia-TFE (MiT) family, including TFEB and TFE3 in mammals and HLH-30 in Caenorhabditis elegans, have emerged as important regulators of innate immunity and inflammation in invertebrates and vertebrates. Despite great strides in knowledge, the m...

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Detalles Bibliográficos
Autores principales: Goswamy, Debanjan, Gonzalez, Xavier, Labed, Sid A., Irazoqui, Javier E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968933/
https://www.ncbi.nlm.nih.gov/pubmed/36860863
http://dx.doi.org/10.3389/fimmu.2023.1094145