Cargando…

Generation of functional human T cell development in NOD/SCID/IL2rγ(null) humanized mice without using fetal tissue: Application as a model of HIV infection and persistence

Humanization of mice with functional T cells currently relies on co-implantation of hematopoietic stem cells from fetal liver and autologous fetal thymic tissue (so-called BLT mouse model). Here, we show that NOD/SCID/IL2rγ(null) mice humanized with cord blood- derived CD34(+) cells and implanted wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Colas, Chloé, Volodina, Olga, Béland, Kathie, Pham, Tram N.Q., Li, Yuanyi, Dallaire, Frédéric, Soulard, Clara, Lemieux, William, Colamartino, Aurélien B.L., Tremblay-Laganière, Camille, Dicaire, Renée, Guimond, Jean, Vobecky, Suzanne, Poirier, Nancy, Patey, Natasha, Cohen, Éric A., Haddad, Elie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Resource
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969074/ https://www.ncbi.nlm.nih.gov/pubmed/36736326 http://dx.doi.org/10.1016/j.stemcr.2023.01.003

Ejemplares similares

Differential Secondary Reconstitution of In Vivo-Selected Human SCID-Repopulating Cells in NOD/SCID versus NOD/SCID/γ chain(null) Mice
por: Cai, Shanbao, et al.
Publicado: (2011)

Comparison of biological features between severely immuno-deficient NOD/Shi-scid Il2rg(null) and NOD/LtSz-scid Il2rg(null) mice
por: Nagatani, Mariko, et al.
Publicado: (2019)

Efficient and Robust NK-Cell Transduction With Baboon Envelope Pseudotyped Lentivector
por: Colamartino, Aurelien B. L., et al.
Publicado: (2019)

Differential Post-Surgical Metastasis and Survival in SCID, NOD-SCID and NOD-SCID-IL-2Rγ(null) Mice with Parental and Subline Variants of Human Breast Cancer: Implications for Host Defense Mechanisms Regulating Metastasis
por: Milsom, Chloe C., et al.
Publicado: (2013)

Fracture Healing Is Delayed in Immunodeficient NOD/scid‑IL2Rγ(c)(null) Mice
por: Rapp, Anna E., et al.
Publicado: (2016)

Spontaneous granulocytic leukemia in a NOD/Shi-scid IL-2Rγ(null) mouse
por: Akane, Hirotoshi, et al.
Publicado: (2021)

Recovery and Biodistribution of Ex Vivo Expanded Human Erythroblasts Injected into NOD/SCID/IL2Rγ(null) mice
por: Ghinassi, Barbara, et al.
Publicado: (2011)

Enhanced development of functional human NK cells in NOD‐ scid‐IL2rg(null) mice expressing human IL15
por: Aryee, Ken‐Edwin, et al.
Publicado: (2022)

Human osteoclastogenesis in Epstein-Barr virus-induced erosive arthritis in humanized NOD/Shi-scid/IL-2Rγ(null) mice
por: Nagasawa, Yosuke, et al.
Publicado: (2021)

Incidence of spontaneous lymphomas in non-experimental NOD/Shi-scid, IL-2Rγ(null) (NOG) mice
por: Yasuda, Masahiko, et al.
Publicado: (2017)

Successful Establishment of an Orthotopic Hepatoblastoma In Vivo Model in NOD/LtSz-scid IL2Rγnull Mice
por: Ellerkamp, Verena, et al.
Publicado: (2011)

Long-Term Engraftment of Human Natural T Regulatory Cells in NOD/SCID IL2rγc(null) Mice by Expression of Human IL-2
por: Abraham, Sojan, et al.
Publicado: (2012)

NOD/scid IL-2Rg(null )mice: a preclinical model system to evaluate human dendritic cell-based vaccine strategies in vivo
por: Spranger, Stefani, et al.
Publicado: (2012)

Assessment of Benzene-Induced Hematotoxicity Using a Human-Like Hematopoietic Lineage in NOD/Shi-scid/IL-2Rγ(null) Mice
por: Takahashi, Masayuki, et al.
Publicado: (2012)

Antibody Repertoires in Humanized NOD-scid-IL2Rγ(null) Mice and Human B Cells Reveals Human-Like Diversification and Tolerance Checkpoints in the Mouse
por: Ippolito, Gregory C., et al.
Publicado: (2012)

Evaluating Human Immune Responses for Vaccine Development in a Novel Human Spleen Cell-Engrafted NOD-SCID-IL2rγNull Mouse Model
por: Ghosn, Stéphanie, et al.
Publicado: (2018)

Dengue Virus Infection and Virus-Specific HLA-A2 Restricted Immune Responses in Humanized NOD-scid IL2rγ(null) Mice
por: Jaiswal, Smita, et al.
Publicado: (2009)

Improved function and proliferation of adult human beta cells engrafted in diabetic immunodeficient NOD-scid IL2rγ(null) mice treated with alogliptin
por: Jurczyk, Agata, et al.
Publicado: (2013)

Induction of oxazolone-mediated features of atopic dermatitis in NOD-scid IL2Rγ(null) mice engrafted with human peripheral blood mononuclear cells
por: Nolte, Thomas, et al.
Publicado: (2013)

Expansion of Activated Memory CD4(+) T Cells Affects Infectivity of CCR5-Tropic HIV-1 in Humanized NOD/SCID/JAK3(null) Mice
por: Terahara, Kazutaka, et al.
Publicado: (2013)

Evaluation of a recombinant measles virus expressing hepatitis C virus envelope proteins by infection of human PBL-NOD/Scid/Jak3null mouse
por: Satoh, Masaaki, et al.
Publicado: (2010)

Xenogeneic Graft-versus-Host-Disease in NOD-scid IL-2Rγ(null) Mice Display a T-Effector Memory Phenotype
por: Ali, Niwa, et al.
Publicado: (2012)

Human B-cell ontogeny in humanized NOD/SCID γc(null) mice generates a diverse yet auto/poly- and HIV-1 reactive antibody repertoire
por: Chang, Hong, et al.
Publicado: (2012)

NOD-scid IL2R γ(null) mice engrafted with human peripheral blood mononuclear cells as a model to test therapeutics targeting human signaling pathways
por: Zadeh-Khorasani, Maryam, et al.
Publicado: (2013)

NOD/scid IL‐2Rγ(null) mice reconstituted with peripheral blood mononuclear cells from patients with Crohn's disease reflect the human pathological phenotype
por: Unterweger, Anna‐Lena, et al.
Publicado: (2021)

IL‐10 induces IgG4 production in NOD‐scid Il2rγ(null) mice humanized by engraftment of peripheral blood mononuclear cells
por: Cevhertas, Lacin, et al.
Publicado: (2021)

Reevaluation of NOD/SCID Mice as NK Cell-Deficient Models
por: Miao, Miao, et al.
Publicado: (2021)

In vivo Effects of a Histone Deacetylase Inhibitor, FK228, on Human Acute Promyelocytic Leukemia in NOD/Shi‐scid/scid Mice
por: Kosugi, Hiroshi, et al.
Publicado: (2001)

Rapid engraftment of human ALL in NOD/SCID mice involves deficient apoptosis signaling
por: Queudeville, M, et al.
Publicado: (2012)

NOD-scidIl2rg(tm1Wjl) and NOD-Rag1(null)Il2rg(tm1Wjl): A Model for Stromal Cell–Tumor Cell Interaction for Human Colon Cancer
por: Maykel, Justin, et al.
Publicado: (2014)

Humanizing NOD/SCID/IL-2Rγnull (NSG) mice using busulfan and retro-orbital injection of umbilical cord blood-derived CD34(+) cells
por: Kang, Young Kyung, et al.
Publicado: (2016)

Transplantation of human umbilical cord blood CD34(+) cells into the liver of newborn NOD/SCID/IL-2Rγ null (NSG) mice after busulfan conditioning
por: Ko, Yunmi, et al.
Publicado: (2017)

Intratibial Injection of Human Multiple Myeloma Cells in NOD/SCID IL-2Rγ(Null) Mice Mimics Human Myeloma and Serves as a Valuable Tool for the Development of Anticancer Strategies
por: Schueler, Julia, et al.
Publicado: (2013)

Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD–scid IL-2rg(null) RIP-DTR mice engrafted with human islets
por: Yang, Chaoxing, et al.
Publicado: (2015)

Neither epithelial nor mesenchymal circulating tumor cells isolated from breast cancer patients are tumorigenic in NOD-scid Il2rg(null) mice
por: Donnenberg, Vera S, et al.
Publicado: (2016)

Spiny mice (Acomys) cells fail to engraft in NOD scid gamma
por: Gaire, Janak, et al.
Publicado: (2023)

Reference genomes for BALB/c Nude and NOD/SCID mouse models
por: Schmid-Siegert, Emanuel, et al.
Publicado: (2023)

Increased Engraftment of Human Short Term Repopulating Hematopoietic Cells in NOD/SCID/IL2rγ(null) Mice by Lentiviral Expression of NUP98-HOXA10HD
por: Abraham, Allistair, et al.
Publicado: (2016)

Engraftment of Human Primary Acute Myeloid Leukemia Defined by Integrated Genetic Profiling in NOD/SCID/IL2rγnull Mice for Preclinical Ceramide-Based Therapeutic Evaluation
por: Barth, Brian M, et al.
Publicado: (2014)

Appearance of Human Plasma Cells Following Differentiation of Human B Cells in NOD/SCID Mouse Spleen
por: Kikuchi, Kentaro, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_uddujmevcalcu2brsa2kestlq3