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Human spinal GABA neurons survive and mature in the injured nonhuman primate spinal cord

Spinal cord injury (SCI) leads to permanent neural dysfunction without effective therapies. We previously showed that human pluripotent stem cell (hPSC)-derived spinal GABA neurons can alleviate spasticity and promote locomotion in rats after SCI, but whether this strategy can be translated into the...

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Detalles Bibliográficos
Autores principales: Zheng, Xiaolong, Zhu, Bo, Xu, Jiang, Liu, Dong, Huang, Yan, Chen, Daiqi, Liu, Zhixian, Guo, Fangliang, Dong, Yuanji, Zhu, Wenzhen, Pan, Dengji, Zhang, Su-Chun, Chen, Hong, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969075/
https://www.ncbi.nlm.nih.gov/pubmed/36669493
http://dx.doi.org/10.1016/j.stemcr.2022.12.016