Cargando…

UBE2S and UBE2C confer a poor prognosis to breast cancer via downregulation of Numb

PURPOSE: Ubiquitin-conjugating enzymes E2S (UBE2S) and E2C (UBE2C), which mediate the biological process of ubiquitination, have been widely reported in various cancers. Numb, the cell fate determinant and tumor suppressor, was also involved in ubiquitination and proteasomal degradation. However, th...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Yanjing, Chen, Xinyu, Zhang, Xiaowei, Hu, Xichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969189/
https://www.ncbi.nlm.nih.gov/pubmed/36860312
http://dx.doi.org/10.3389/fonc.2023.992233