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C3a-C3aR signaling is a novel modulator of skeletal homeostasis

Osteoimmune studies have identified complement signaling as an important regulator of the skeleton. Specifically, complement anaphylatoxin receptors (i.e., C3aR, C5aR) are expressed on osteoblasts and osteoclasts, implying that C3a and/or C5a may be candidate mediators of skeletal homeostasis. The s...

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Detalles Bibliográficos
Autores principales: Kuhn, Megan B., VandenBerg, Hayden S., Reynolds, Andrew J., Carson, Matthew D., Warner, Amy J., LaRue, Amanda C., Novince, Chad M., Hathaway-Schrader, Jessica D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969257/
https://www.ncbi.nlm.nih.gov/pubmed/36860797
http://dx.doi.org/10.1016/j.bonr.2023.101662