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Salmonella Typhimurium expressing chromosomally integrated Schistosoma mansoni Cathepsin B protects against schistosomiasis in mice

Schistosomiasis threatens hundreds of millions of people worldwide. The larval stage of Schistosoma mansoni migrates through the lung and adult worms reside adjacent to the colonic mucosa. Several candidate vaccines are in preclinical development, but none is designed to elicit both systemic and muc...

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Detalles Bibliográficos
Autores principales: Hassan, Adam S., Houle, Sébastien, Labrie, Lydia, Perera, Dilhan J., Dozois, Charles M., Ward, Brian J., Ndao, Momar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969381/
https://www.ncbi.nlm.nih.gov/pubmed/36849453
http://dx.doi.org/10.1038/s41541-023-00599-w