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An investigation of binding interactions of tumor-targeted peptide conjugated polyphenols with the kinase domain of ephrin B4 and B2 receptors

ABSTRACT: Recent studies have shown that Ephrin receptors may be upregulated in several types of cancers including breast, ovarian and endometrial cancers, making them a target for drug design. In this work, we have utilized a target-hopping approach to design new natural product-peptide conjugates...

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Detalles Bibliográficos
Autores principales: Mitchell, Saige M., Heise, Ryan M., Murray, Molly E., Lambo, Dominic J., Daso, Rachel E., Banerjee, Ipsita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969393/
https://www.ncbi.nlm.nih.gov/pubmed/36847923
http://dx.doi.org/10.1007/s11030-023-10621-x