Cargando…
Rhenium(V) Complexes as Cysteine-Targeting Coordinate Covalent Warheads
[Image: see text] Interest in covalent enzyme inhibitors as therapeutic agents has seen a recent resurgence. Covalent enzyme inhibitors typically possess an organic functional group that reacts with a key feature of the target enzyme, often a nucleophilic cysteine residue. Herein, the application of...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969397/ https://www.ncbi.nlm.nih.gov/pubmed/36752718 http://dx.doi.org/10.1021/acs.jmedchem.2c02074 |