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Thioredoxin-1 Promotes Mitochondrial Biogenesis Through Regulating AMPK/Sirt1/PGC1α Pathway in Alzheimer's Disease

Alzheimer's disease (AD) is the most common neurodegenerative disease. Increasing studies suggest that mitochondrial dysfunction is closely related to the pathogenesis of AD. Thioredoxin-1 (Trx-1), one of the major redox proteins in mammalian cells, plays neuroprotection in AD. However, whether...

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Detalles Bibliográficos
Autores principales: Jia, Jinjing, Yin, Jiayi, Zhang, Yu, Xu, Guangtao, Wang, Min, Jiang, Haiying, Li, Li, Zeng, Xiansi, Zhu, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969465/
https://www.ncbi.nlm.nih.gov/pubmed/36823760
http://dx.doi.org/10.1177/17590914231159226