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Exogenous Lipoxin A4 attenuates IL4-induced Mucin Expression in Human Airway Epithelial Cells

Introduction: The proinflammatory cytokine interleukin-4 (IL-4) induces mucus hypersecretion by human airway epithelial cells and the MAP kinase signalling pathway may be important in terms of IL-4-induced MUC5AC gene expression. Lipoxin A(4) (LXA(4)) is an arachidonic acid-derived mediator that pro...

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Detalles Bibliográficos
Autores principales: Seo, Eun-Hye, Lee, Seung Hyun, Choi, Bo Yoon, Oh, Chung-Sik, Kim, Jin Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969498/
https://www.ncbi.nlm.nih.gov/pubmed/36860679
http://dx.doi.org/10.7150/ijms.79525