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Oncogenic and Receptor-Mediated Wnt Signaling Influence the Sensitivity of Colonic Cells to Butyrate
Deregulated Wnt signaling is responsible for most cases of colorectal cancer (CRC). Dietary fiber is protective against CRC and this activity is likely mediated by butyrate, a breakdown product of dietary fiber that hyperactivates Wnt signaling, repressing CRC proliferation and inducing apoptosis. R...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Ivyspring International Publisher
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969577/ https://www.ncbi.nlm.nih.gov/pubmed/36860917 http://dx.doi.org/10.7150/jca.82393 |