Efficacy of a Novel Pleiotropic MMP-Inhibitor, CMC2.24, in a Long-Term Diabetes Rat Model with Severe Hyperglycemia-Induced Oral Bone Loss

PURPOSE: CMC2.24, a novel 4-(phenylaminocarbonyl)-chemically-modified-curcumin, is a pleiotropic MMP-Inhibitor of various inflammatory/collagenolytic diseases including periodontitis. This compound has demonstrated efficacy in host modulation therapy along with improved resolution of inflammation in...

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Detalles Bibliográficos
Autores principales: Bhatt, Heta Dinesh, Golub, Lorne M, Lee, Hsi-Ming, Kim, Jihwan, Zimmerman, Thomas, Deng, Jie, Hong, Houlin, Johnson, Francis, Gu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969803/
https://www.ncbi.nlm.nih.gov/pubmed/36860795
http://dx.doi.org/10.2147/JIR.S399043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969803/
https://www.ncbi.nlm.nih.gov/pubmed/36860795
http://dx.doi.org/10.2147/JIR.S399043

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