LDmat: efficiently queryable compression of linkage disequilibrium matrices

MOTIVATION: Linkage disequilibrium (LD) matrices derived from large populations are widely used in population genetics in fine-mapping, LD score regression, and linear mixed models for Genome-wide Association Studies (GWAS). However, these matrices can reach large sizes when they are derived from mi...

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Detalles Bibliográficos
Autores principales: Weiner, Rockwell J, Lakhani, Chirag, Knowles, David A, Gürsoy, Gamze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969815/
https://www.ncbi.nlm.nih.gov/pubmed/36794924
http://dx.doi.org/10.1093/bioinformatics/btad092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969815/
https://www.ncbi.nlm.nih.gov/pubmed/36794924
http://dx.doi.org/10.1093/bioinformatics/btad092

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