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LDmat: efficiently queryable compression of linkage disequilibrium matrices
MOTIVATION: Linkage disequilibrium (LD) matrices derived from large populations are widely used in population genetics in fine-mapping, LD score regression, and linear mixed models for Genome-wide Association Studies (GWAS). However, these matrices can reach large sizes when they are derived from mi...
Autores principales: | Weiner, Rockwell J, Lakhani, Chirag, Knowles, David A, Gürsoy, Gamze |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969815/ https://www.ncbi.nlm.nih.gov/pubmed/36794924 http://dx.doi.org/10.1093/bioinformatics/btad092 |
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