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α-Mangostin Inhibited M1 Polarization of Macrophages/Monocytes in Antigen-Induced Arthritis Mice by Up-Regulating Silent Information Regulator 1 and Peroxisome Proliferators-Activated Receptor γ Simultaneously

BACKGROUND: α-Mangostin (MG) showed the potentials in alleviating experimental arthritis, inhibiting inflammatory polarization of macrophages/monocytes, and regulating peroxisome proliferators-activated receptor γ (PPAR-γ) and silent information regulator 1 (SIRT1) signals. The aim of this study was...

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Detalles Bibliográficos
Autores principales: Wu, Yi-Jin, Zhang, Sa-Sa, Yin, Qin, Lei, Ming, Wang, Qi-Hai, Chen, Wen-Gang, Luo, Ting-Ting, Zhou, Peng, Ji, Cong-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969869/
https://www.ncbi.nlm.nih.gov/pubmed/36860800
http://dx.doi.org/10.2147/DDDT.S397914