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Single-cell transcriptome analysis reveals the metabolic changes and the prognostic value of malignant hepatocyte subpopulations and predict new therapeutic agents for hepatocellular carcinoma

BACKGROUND: The development of HCC is often associated with extensive metabolic disturbances. Single cell RNA sequencing (scRNA-seq) provides a better understanding of cellular behavior in the context of complex tumor microenvironments by analyzing individual cell populations. METHODS: The Cancer Ge...

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Detalles Bibliográficos
Autores principales: Han, Cuifang, Chen, Jiaru, Huang, Jing, Zhu, Riting, Zeng, Jincheng, Yu, Hongbing, He, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969971/
https://www.ncbi.nlm.nih.gov/pubmed/36860314
http://dx.doi.org/10.3389/fonc.2023.1104262