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Mechanisms and Consequences of Variable TRPA1 Expression by Airway Epithelial Cells: Effects of TRPV1 Genotype and Environmental Agonists on Cellular Responses to Pollutants in Vitro and Asthma

BACKGROUND: Transient receptor potential ankyrin-1 [transient receptor potential cation channel subfamily A member 1 (TRPA1)] and vanilloid-1 [transient receptor potential cation channel subfamily V member 1 (TRPV1)] detect inhaled irritants, including air pollutants and have roles in the developmen...

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Detalles Bibliográficos
Autores principales: Rapp, Emmanuel, Lu, Zhenyu, Sun, Lili, Serna, Samantha N., Almestica-Roberts, Marysol, Burrell, Katherine L., Nguyen, Nam D., Deering-Rice, Cassandra E., Reilly, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969990/
https://www.ncbi.nlm.nih.gov/pubmed/36847817
http://dx.doi.org/10.1289/EHP11076