VGLL4 and MENIN function as TEAD1 corepressors to block pancreatic β cell proliferation

TEAD1 and the mammalian Hippo pathway regulate cellular proliferation and function, though their regulatory function in β cells remains poorly characterized. In this study, we demonstrate that while β cell-specific TEAD1 deletion results in a cell-autonomous increase of β cell proliferation, β cell-...

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Detalles Bibliográficos
Autores principales: Li, Feng, Liu, Ruya, Negi, Vinny, Yang, Ping, Lee, Jeongkyung, Jagannathan, Rajaganapathi, Moulik, Mousumi, Yechoor, Vijay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970006/
https://www.ncbi.nlm.nih.gov/pubmed/36662616
http://dx.doi.org/10.1016/j.celrep.2022.111904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970006/
https://www.ncbi.nlm.nih.gov/pubmed/36662616
http://dx.doi.org/10.1016/j.celrep.2022.111904

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