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VGLL4 and MENIN function as TEAD1 corepressors to block pancreatic β cell proliferation
TEAD1 and the mammalian Hippo pathway regulate cellular proliferation and function, though their regulatory function in β cells remains poorly characterized. In this study, we demonstrate that while β cell-specific TEAD1 deletion results in a cell-autonomous increase of β cell proliferation, β cell-...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970006/ https://www.ncbi.nlm.nih.gov/pubmed/36662616 http://dx.doi.org/10.1016/j.celrep.2022.111904 |