Involvement and possible role of transglutaminases 1 and 2 in mediating fibrotic signalling, collagen cross-linking and cell proliferation in neonatal rat ventricular fibroblasts

Transglutaminase (TG) isoforms control diverse normal and pathophysiologic processes through their capacity to cross-link extracellular matrix (ECM) proteins. Their functional and signalling roles in cardiac fibrosis remain poorly understood, despite some evidence of TG2 involvement in abnormal ECM...

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Detalles Bibliográficos
Autores principales: Al-U’datt, Doa’a G. F., Tranchant, Carole C., Al-Husein, Belal, Hiram, Roddy, Al-Dwairi, Ahmed, AlQudah, Mohammad, Al-shboul, Othman, Jaradat, Saied, Alqbelat, Jenan, Almajwal, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970086/
https://www.ncbi.nlm.nih.gov/pubmed/36848364
http://dx.doi.org/10.1371/journal.pone.0281320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970086/
https://www.ncbi.nlm.nih.gov/pubmed/36848364
http://dx.doi.org/10.1371/journal.pone.0281320

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