Tumor microenvironment-responsive micelles assembled from a prodrug of mitoxantrone and 1-methyl tryptophan for enhanced chemo-immunotherapy

Mitoxantrone (MX) can induce the immunogenic-cell death (ICD) of tumor cells and activate anti-tumor immune responses. However, it can also cause high expression of indole amine 2, 3-dioxygenase (IDO) during ICD, leading to T-cell apoptosis and a weakened immune response. An IDO inhibitor, 1-methyl...

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Detalles Bibliográficos
Autores principales: Wang, Ru, Li, Nuannuan, Zhang, Tianyu, Sun, Yiying, He, Xiaoyan, Lu, Xiaoyan, Chu, Liuxiang, Sun, Kaoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970211/
https://www.ncbi.nlm.nih.gov/pubmed/36840464
http://dx.doi.org/10.1080/10717544.2023.2182254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970211/
https://www.ncbi.nlm.nih.gov/pubmed/36840464
http://dx.doi.org/10.1080/10717544.2023.2182254

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