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COVID-19 mRNA vaccine protects against SARS-CoV-2 Omicron BA.1 infection in diet-induced obese mice through boosting host innate antiviral responses

BACKGROUND: Obesity is a worldwide epidemic and is considered a risk factor of severe manifestation of Coronavirus Disease 2019 (COVID-19). The pathogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and host responses to infection, re-infection, and vaccination in individuals...

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Detalles Bibliográficos
Autores principales: Chen, Yanxia, Song, Wenchen, Li, Can, Wang, Jiaxuan, Liu, Feifei, Ye, Zhanhong, Ren, Peidi, Tong, Yihan, Li, Junhua, Ou, Zhihua, Lee, Andrew Chak-Yiu, Cai, Jian-Piao, Wong, Bosco Ho-Yin, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung, Zhang, Anna Jin-Xia, Chu, Hin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970285/
https://www.ncbi.nlm.nih.gov/pubmed/36857860
http://dx.doi.org/10.1016/j.ebiom.2023.104485