Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity

Background: Metformin, a commonly prescribed anti-diabetic medication, has repeatedly been shown to hinder aging in pre-clinical models and to be associated with lower mortality for humans. It is, however, not well understood how metformin can potentially prolong lifespan from a biological standpoin...

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Detalles Bibliográficos
Autores principales: Marra, Pedro S., Yamanashi, Takehiko, Crutchley, Kaitlyn J., Wahba, Nadia E., Anderson, Zoe-Ella M., Modukuri, Manisha, Chang, Gloria, Tran, Tammy, Iwata, Masaaki, Cho, Hyunkeun Ryan, Shinozaki, Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970305/
https://www.ncbi.nlm.nih.gov/pubmed/36734879
http://dx.doi.org/10.18632/aging.204498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970305/
https://www.ncbi.nlm.nih.gov/pubmed/36734879
http://dx.doi.org/10.18632/aging.204498

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