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The lipidomes of C. elegans with mutations in asm-3/acid sphingomyelinase and hyl-2/ceramide synthase show distinct lipid profiles during aging

Lipid metabolism affects cell and physiological functions that mediate animal healthspan and lifespan. Lipidomics approaches in model organisms have allowed us to better understand changes in lipid composition related to age and lifespan. Here, using the model C. elegans, we examine the lipidomes of...

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Detalles Bibliográficos
Autores principales: Staab, Trisha A., McIntyre, Grace, Wang, Lu, Radeny, Joycelyn, Bettcher, Lisa, Guillen, Melissa, Peck, Margaret P., Kalil, Azia P., Bromley, Samantha P., Raftery, Daniel, Chan, Jason P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970312/
https://www.ncbi.nlm.nih.gov/pubmed/36787434
http://dx.doi.org/10.18632/aging.204515