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Lactate as a myokine and exerkine: drivers and signals of physiology and metabolism

No longer viewed as a metabolic waste product and cause of muscle fatigue, a contemporary view incorporates the roles of lactate in metabolism, sensing and signaling in normal as well as pathophysiological conditions. Lactate exists in millimolar concentrations in muscle, blood, and other tissues an...

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Detalles Bibliográficos
Autores principales: Brooks, George A., Osmond, Adam D., Arevalo, Jose A., Duong, Justin J., Curl, Casey C., Moreno-Santillan, Diana D., Leija, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970662/
https://www.ncbi.nlm.nih.gov/pubmed/36633863
http://dx.doi.org/10.1152/japplphysiol.00497.2022