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Extracellular Vesicles Derived from Three-Dimensional-Cultured Human Umbilical Cord Blood Mesenchymal Stem Cells Prevent Inflammation and Dedifferentiation in Pancreatic Islets

It is unclear whether extracellular vesicles (EVs) from mesenchymal stem cells (MSCs) have a direct protective effect on pancreatic islets. In addition, whether culturing MSCs in three dimensions (3D) instead of a monolayer (2D) can induce changes in the cargo of EVs that facilitate the polarization...

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Detalles Bibliográficos
Autores principales: Lee, Eunwon, Ha, Seungyeon, Kim, Gyuri, Kim, Jae Hyeon, Jin, Sang-Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970714/
https://www.ncbi.nlm.nih.gov/pubmed/36860546
http://dx.doi.org/10.1155/2023/5475212