Picropodophyllotoxin Inhibits Cell Growth and Induces Apoptosis in Gefitinib-Resistant Non-Small Lung Cancer Cells by Dual-Targeting EGFR and MET

Patients with non-small-cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) amplification or sensitive mutations initially respond to the tyrosine kinase inhibitor gefitinib, however, the treatment becomes less effective over time by resistance mechanism including mesenchymal-epith...

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Detalles Bibliográficos
Autores principales: Lee, Jin-Young, Kang, Bok Yun, Jung, Sang-Jin, Kwak, Ah-Won, Lee, Seung-On, Park, Jin Woo, Joo, Sang Hoon, Yoon, Goo, Lee, Mee-Hyun, Shim, Jung-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970835/
https://www.ncbi.nlm.nih.gov/pubmed/36281696
http://dx.doi.org/10.4062/biomolther.2022.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970835/
https://www.ncbi.nlm.nih.gov/pubmed/36281696
http://dx.doi.org/10.4062/biomolther.2022.113

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