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Structure–Activity Relationship and Evaluation of Phenethylamine and Tryptamine Derivatives for Affinity towards 5-Hydroxytryptamine Type 2A Receptor

Among 14 subtypes of serotonin receptors (5-HTRs), 5-HT(2A)R plays important roles in drug addiction and various psychiatric disorders. Agonists for 5-HT(2A)R have been classified into three structural groups: phenethylamines, tryptamines, and ergolines. In this study, the structure-activity relatio...

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Detalles Bibliográficos
Autores principales: Wang, Shujie, Zhu, Anlin, Paudel, Suresh, Jang, Choon-Gon, Lee, Yong Sup, Kim, Kyeong-Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970836/
https://www.ncbi.nlm.nih.gov/pubmed/36224112
http://dx.doi.org/10.4062/biomolther.2022.096