Megakaryocyte-Derived IL-8 Acts as a Paracrine Factor for Prostate Cancer Aggressiveness through CXCR2 Activation and Antagonistic AR Downregulation

Prostate cancer is the fifth leading cause of cancer-related mortality in men, primarily because of treatment resistance, recurrence, and metastasis. In the present study, we investigated the role of paracrine interleukin-8 (IL-8) in the antagonistic expression of IL-8 and androgen receptor (AR), an...

Descripción completa

Detalles Bibliográficos
Autores principales: Dahal, Sadan, Chaudhary, Prakash, Jung, Yi-Sook, Kim, Jung-Ae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970838/
https://www.ncbi.nlm.nih.gov/pubmed/36787954
http://dx.doi.org/10.4062/biomolther.2023.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970838/
https://www.ncbi.nlm.nih.gov/pubmed/36787954
http://dx.doi.org/10.4062/biomolther.2023.005

Ejemplares similares