Tramadol as a Voltage-Gated Sodium Channel Blocker of Peripheral Sodium Channels Na(v)1.7 and Na(v)1.5

Tramadol is an opioid analog used to treat chronic and acute pain. Intradermal injections of tramadol at hundreds of millimoles have been shown to produce a local anesthetic effect. We used the whole-cell patch-clamp technique in this study to investigate whether tramadol blocks the sodium current i...

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Detalles Bibliográficos
Autores principales: Bok, Chan-Su, Kim, Ryeong-Eun, Cho, Yong-Yeon, Choi, Jin-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970842/
https://www.ncbi.nlm.nih.gov/pubmed/36779240
http://dx.doi.org/10.4062/biomolther.2023.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970842/
https://www.ncbi.nlm.nih.gov/pubmed/36779240
http://dx.doi.org/10.4062/biomolther.2023.002

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