Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers

Analysis of mutational signatures can reveal underlying molecular mechanisms of the processes that have imprinted the somatic mutations found in cancer genomes. Here, we analyze single base substitutions and small insertions and deletions in pediatric cancers encompassing 785 whole-genome sequenced...

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Detalles Bibliográficos
Autores principales: Thatikonda, Venu, Islam, S. M. Ashiqul, Autry, Robert J., Jones, Barbara C., Gröbner, Susanne N., Warsow, Gregor, Hutter, Barbara, Huebschmann, Daniel, Fröhling, Stefan, Kool, Marcel, Blattner-Johnson, Mirjam, Jones, David T. W., Alexandrov, Ludmil B., Pfister, Stefan M., Jäger, Natalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970869/
https://www.ncbi.nlm.nih.gov/pubmed/36702933
http://dx.doi.org/10.1038/s43018-022-00509-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970869/
https://www.ncbi.nlm.nih.gov/pubmed/36702933
http://dx.doi.org/10.1038/s43018-022-00509-4

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