Integrative multi-omics networks identify PKCδ and DNA-PK as master kinases of glioblastoma subtypes and guide targeted cancer therapy

Despite producing a panoply of potential cancer-specific targets, the proteogenomic characterization of human tumors has yet to demonstrate value for precision cancer medicine. Integrative multi-omics using a machine-learning network identified master kinases responsible for effecting phenotypic hal...

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Detalles Bibliográficos
Autores principales: Migliozzi, Simona, Oh, Young Taek, Hasanain, Mohammad, Garofano, Luciano, D’Angelo, Fulvio, Najac, Ryan D., Picca, Alberto, Bielle, Franck, Di Stefano, Anna Luisa, Lerond, Julie, Sarkaria, Jann N., Ceccarelli, Michele, Sanson, Marc, Lasorella, Anna, Iavarone, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970878/
https://www.ncbi.nlm.nih.gov/pubmed/36732634
http://dx.doi.org/10.1038/s43018-022-00510-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970878/
https://www.ncbi.nlm.nih.gov/pubmed/36732634
http://dx.doi.org/10.1038/s43018-022-00510-x

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