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Cost effective and reliable cell based ELISA as an alternative method of flow cytometry for assessment of binding activity of Vedolizumab

Vedolizumab is a humanized monoclonal antibody used for inflammatory bowel disease treatment. Vedolizumab binds to the α4β7 integrin complex and inhibits its binding to mucosal addressin cell adhesion molecule-1 (MAdCAM-1). To evaluate the binding efficacy and quality control check of Vedolizumab, f...

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Detalles Bibliográficos
Autores principales: Shalini, Swati, Sharma, Anu, Mishra, Nripendra Nath, Sharma, Ratnesh Kumar, Chander, Harish, Anvikar, Anupkumar R., Chand, Subhash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970907/
https://www.ncbi.nlm.nih.gov/pubmed/36865445
http://dx.doi.org/10.1016/j.heliyon.2023.e13570