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SARS-CoV-2 breakthrough infection induces rapid memory and de novo T cell responses

Although the protective role of neutralizing antibodies against COVID-19 is well established, questions remain about the relative importance of cellular immunity. Using 6 pMHC multimers in a cohort with early and frequent sampling, we define the phenotype and kinetics of recalled and primary T cell...

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Detalles Bibliográficos
Autores principales: Koutsakos, Marios, Reynaldi, Arnold, Lee, Wen Shi, Nguyen, Julie, Amarasena, Thakshila, Taiaroa, George, Kinsella, Paul, Liew, Kwee Chin, Tran, Thomas, Kent, Helen E., Tan, Hyon-Xhi, Rowntree, Louise C., Nguyen, Thi H.O., Thomas, Paul G., Kedzierska, Katherine, Petersen, Jan, Rossjohn, Jamie, Williamson, Deborah A., Khoury, David, Davenport, Miles P., Kent, Stephen J., Wheatley, Adam K., Juno, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970913/
https://www.ncbi.nlm.nih.gov/pubmed/36958334
http://dx.doi.org/10.1016/j.immuni.2023.02.017