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SARS-CoV-2 breakthrough infection induces rapid memory and de novo T cell responses
Although the protective role of neutralizing antibodies against COVID-19 is well established, questions remain about the relative importance of cellular immunity. Using 6 pMHC multimers in a cohort with early and frequent sampling, we define the phenotype and kinetics of recalled and primary T cell...
Autores principales: | Koutsakos, Marios, Reynaldi, Arnold, Lee, Wen Shi, Nguyen, Julie, Amarasena, Thakshila, Taiaroa, George, Kinsella, Paul, Liew, Kwee Chin, Tran, Thomas, Kent, Helen E., Tan, Hyon-Xhi, Rowntree, Louise C., Nguyen, Thi H.O., Thomas, Paul G., Kedzierska, Katherine, Petersen, Jan, Rossjohn, Jamie, Williamson, Deborah A., Khoury, David, Davenport, Miles P., Kent, Stephen J., Wheatley, Adam K., Juno, Jennifer A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970913/ https://www.ncbi.nlm.nih.gov/pubmed/36958334 http://dx.doi.org/10.1016/j.immuni.2023.02.017 |
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