Inhibition of nicotinamide dinucleotide salvage pathway counters acquired and intrinsic poly(ADP-ribose) polymerase inhibitor resistance in high-grade serous ovarian cancer

Epithelial ovarian cancer is the most lethal gynecological malignancy, owing notably to its high rate of therapy-resistant recurrence in spite of good initial response to chemotherapy. Although poly(ADP-ribose) polymerase inhibitors (PARPi) have shown promise for ovarian cancer treatment, extended t...

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Detalles Bibliográficos
Autores principales: Sauriol, Alexandre, Carmona, Euridice, Udaskin, Molly L., Radulovich, Nikolina, Leclerc-Desaulniers, Kim, Rottapel, Robert, Oza, Amit M., Lheureux, Stephanie, Provencher, Diane M., Mes-Masson, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970983/
https://www.ncbi.nlm.nih.gov/pubmed/36849518
http://dx.doi.org/10.1038/s41598-023-30081-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970983/
https://www.ncbi.nlm.nih.gov/pubmed/36849518
http://dx.doi.org/10.1038/s41598-023-30081-5

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