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Kaixin-San improves Aβ-induced synaptic plasticity inhibition by affecting the expression of regulation proteins associated with postsynaptic AMPAR expression

Objective: To explore the mechanism underlying Kaixin-San (KXS) regulation of postsynaptic AMPA receptor (AMPAR) expression to mitigate toxic effects of the amyloid-β protein (Aβ). Methods: An animal model was established via intracerebroventricular injection of Aβ1–42. The Morris water maze test wa...

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Detalles Bibliográficos
Autores principales: Zhang, Bo, Wang, Meng-Lu, Huang, Shu-Ming, Cui, Yu, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970989/
https://www.ncbi.nlm.nih.gov/pubmed/36865910
http://dx.doi.org/10.3389/fphar.2023.1079400