Orthodenticle homeobox 2 is transported to lysosomes by nuclear budding vesicles

Transcription factors (TFs) are transported from the cytoplasm to the nucleus and disappear from the nucleus after they regulate gene expression. Here, we discover an unconventional nuclear export of the TF, orthodenticle homeobox 2 (OTX2), in nuclear budding vesicles, which transport OTX2 to the ly...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Jun Woo, Lee, Eun Jung, Moon, Eunyoung, Kim, Hong-Lim, Kim, In-Beom, Hodzic, Didier, Kim, Namsuk, Kweon, Hee-Seok, Kim, Jin Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971051/
https://www.ncbi.nlm.nih.gov/pubmed/36849521
http://dx.doi.org/10.1038/s41467-023-36697-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971051/
https://www.ncbi.nlm.nih.gov/pubmed/36849521
http://dx.doi.org/10.1038/s41467-023-36697-5

Ejemplares similares