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Orthodenticle homeobox 2 is transported to lysosomes by nuclear budding vesicles
Transcription factors (TFs) are transported from the cytoplasm to the nucleus and disappear from the nucleus after they regulate gene expression. Here, we discover an unconventional nuclear export of the TF, orthodenticle homeobox 2 (OTX2), in nuclear budding vesicles, which transport OTX2 to the ly...
Autores principales: | Park, Jun Woo, Lee, Eun Jung, Moon, Eunyoung, Kim, Hong-Lim, Kim, In-Beom, Hodzic, Didier, Kim, Namsuk, Kweon, Hee-Seok, Kim, Jin Woo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971051/ https://www.ncbi.nlm.nih.gov/pubmed/36849521 http://dx.doi.org/10.1038/s41467-023-36697-5 |
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