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Hypoxia-Inducible Factor-1α Protects Against Intervertebral Disc Degeneration Through Antagonizing Mitochondrial Oxidative Stress

Intervertebral disc degeneration (IVDD) demonstrates a gradually increased incidence and has developed into a major health problem worldwide. The nucleus pulposus is characterized by the hypoxic and avascular environment, in which hypoxia-inducible factor-1α (HIF-1α) has an important role through it...

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Detalles Bibliográficos
Autores principales: Yang, Wen, Jia, Chunwang, Liu, Long, Fu, Yu, Wu, Yawei, Liu, Zhicheng, Yu, Ruixuan, Ma, Xiaojie, Gong, Ao, Liu, Fangming, Xia, Yanni, Hou, Yong, Li, Yuhua, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971142/
https://www.ncbi.nlm.nih.gov/pubmed/36064808
http://dx.doi.org/10.1007/s10753-022-01732-y