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Three-dimensional growth reveals fine-tuning of 5-lipoxygenase by proliferative pathways in cancer

The leukotriene (LT) pathway is positively correlated with the progression of solid malignancies, but the factors that control the expression of 5-lipoxygenase (5-LO), the central enzyme in LT biosynthesis, in tumors are poorly understood. Here, we report that 5-LO along with other members of the LT...

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Detalles Bibliográficos
Autores principales: Göbel, Tamara, Goebel, Bjarne, Hyprath, Marius, Lamminger, Ira, Weisser, Hannah, Angioni, Carlo, Mathes, Marius, Thomas, Dominique, Kahnt, Astrid S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971161/
https://www.ncbi.nlm.nih.gov/pubmed/36849252
http://dx.doi.org/10.26508/lsa.202201804