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Loss of SLC26A3 Results in Colonic Mucosal Immune Dysregulation via Epithelial-Immune Cell Crosstalk

BACKGROUND & AIMS: Down-regulation of chloride transporter SLC26A3 or down-regulated in adenoma (DRA) in colonocytes has recently been linked to the pathogenesis of ulcerative colitis (UC). Because exaggerated immune responses are one of the hallmarks of UC, these current studies were undertaken...

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Detalles Bibliográficos
Autores principales: Jayawardena, Dulari, Priyamvada, Shubha, Kageyama, Takahiro, White, Zachary, Kumar, Anoop, Griggs, Theodor F., Majumder, Apurba, Akram, Ramsha, Anbazhagan, Arivarasu N., Sano, Teruyuki, Dudeja, Pradeep K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971172/
https://www.ncbi.nlm.nih.gov/pubmed/36535508
http://dx.doi.org/10.1016/j.jcmgh.2022.12.009