Residue-specific binding of Ni(II) ions influences the structure and aggregation of amyloid beta (Aβ) peptides

Alzheimer’s disease (AD) is the most common cause of dementia worldwide. AD brains display deposits of insoluble amyloid plaques consisting mainly of aggregated amyloid-β (Aβ) peptides, and Aβ oligomers are likely a toxic species in AD pathology. AD patients display altered metal homeostasis, and AD...

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Detalles Bibliográficos
Autores principales: Berntsson, Elina, Vosough, Faraz, Svantesson, Teodor, Pansieri, Jonathan, Iashchishyn, Igor A., Ostojić, Lucija, Dong, Xiaolin, Paul, Suman, Jarvet, Jüri, Roos, Per M., Barth, Andreas, Morozova-Roche, Ludmilla A., Gräslund, Astrid, Wärmländer, Sebastian K. T. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971182/
https://www.ncbi.nlm.nih.gov/pubmed/36849796
http://dx.doi.org/10.1038/s41598-023-29901-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971182/
https://www.ncbi.nlm.nih.gov/pubmed/36849796
http://dx.doi.org/10.1038/s41598-023-29901-5

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