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The UDPase ENTPD5 regulates ER stress-associated renal injury by mediating protein N-glycosylation

Impaired protein N-glycosylation leads to the endoplasmic reticulum (ER) stress, which triggers adaptive survival or maladaptive apoptosis in renal tubules in diabetic kidney disease (DKD). Therapeutic strategies targeting ER stress are promising for the treatment of DKD. Here, we report a previousl...

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Detalles Bibliográficos
Autores principales: Xu, Lifen, Zhou, Yuxia, Wang, Guifang, Bo, Li, Jin, Bangming, Dai, Lujun, Lu, Qinli, Cai, Xueni, Hu, Laying, Liu, Lu, Wu, Yixuan, Chang, Xuebing, Huang, Yali, Song, Lingyu, Zhang, Tian, Wang, Yuanyuan, Xiao, Ying, Zhang, Fan, Liu, Lingling, Shi, Mingjun, Wang, Tuanlao, Guo, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971188/
https://www.ncbi.nlm.nih.gov/pubmed/36849424
http://dx.doi.org/10.1038/s41419-023-05685-4