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CEMIP, acting as a scaffold protein for bridging GRAF1 and MIB1, promotes colorectal cancer metastasis via activating CDC42/MAPK pathway

Metastasis is the leading cause of treatment failure and tumor-related death in colorectal cancer (CRC). Our previous studies report that CEMIP functionally promotes CRC metastasis and is closely related to poor outcomes. However, the molecular network of CEMIP promoting CRC metastasis is still not...

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Detalles Bibliográficos
Autores principales: Xu, Guojie, Zhao, Lei, Hua, Qingling, Wang, Lanqing, Liu, Hongli, Lin, Zhenyu, Jin, Min, Wang, Jing, Zhou, Pengfei, Yang, Kunyu, Wu, Gang, Yu, Dandan, Zhang, Dejun, Zhang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971195/
https://www.ncbi.nlm.nih.gov/pubmed/36849460
http://dx.doi.org/10.1038/s41419-023-05644-z