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Sodium benzoate attenuates 2,8-dihydroxyadenine nephropathy by inhibiting monocyte/macrophage TNF-α expression

Sodium benzoate (SB), a known D-amino acid oxidase (DAO) enzyme inhibitor, has an anti-inflammatory effect, although its role in renal damage has not been explored. 2,8-dihydroxyadenine crystal induced chronic kidney disease, in which TNF-α is involved in the pathogenesis, was established by oral ad...

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Detalles Bibliográficos
Autores principales: Oshima, Yoichi, Wakino, Shu, Kanda, Takeshi, Tajima, Takaya, Itoh, Tomoaki, Uchiyama, Kiyotaka, Yoshimoto, Keiko, Sasabe, Jumpei, Yasui, Masato, Itoh, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971245/
https://www.ncbi.nlm.nih.gov/pubmed/36849798
http://dx.doi.org/10.1038/s41598-023-30056-6